Registration Dossier

Diss Factsheets

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
Media:
soil/sewage sludge
Radiolabelling:
no
Test temperature:
25 °C (column temperature)
Details on study design: HPLC method:
A limit test was performed as a high logKoc value was anticipated. A solution of the test material (approximately 0.3 g/l in mobile phase) was prepared and chromatographed alongside the reference substance DDT.

EQUIPMENT
- Apparatus:
- Type: Hewlett Packard 1050 Series Liquid Chromatograph
- Type, material and dimension of analytical (guard) column: HyperClone CN (CPS) (25 cm x 4.6 mm internal diameter)
- Detection system: UV set at 210 nm

MOBILE PHASES
- Type: Tetrahydrofuran:water (55:45 v/v)
- Experiments with additives carried out on separate columns: no additives used
- pH: no data
- Solutes for dissolving test and reference substances: HPLC mobile phase

DETERMINATION OF DEAD TIME
- Method: by inert substance which is not retained by the column

REFERENCE SUBSTANCES
- Identity: DDT
- Known logKoc value: 5.6

DETERMINATION OF RETENTION TIMES
- Quantity of test substance introduced in the column: 30 µg
- Quantity of reference substances: not reported
- Intervals of calibration: not reported

REPETITIONS
- Number of determinations: not reported

EVALUATION
- Determination of the log Koc value: comparison with the retention time of the reference substance DDT
Key result
Type:
log Koc
Value:
> 5.6
Temp.:
25 °C
Details on results (HPLC method):
The retention times of the main components of the test substance were greater than that of DDT under the test conditions.
Validity criteria fulfilled:
not applicable

Description of key information

Log Koc at 25 °C: > 5.6 (HPLC method; OECD TGD 121, EU Method C.19)

Key value for chemical safety assessment

Additional information

Log Koc at 25°C: > 5.6