Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: conducted to OECD/EC guidelines with GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Hydroxyphosponoaceic acid, trisodium salt (TK13061/2)
- Physical state: Solid (white powder)
- Lot/batch No.: LIC 613/04
- Storage condition of test material: Room temperature in the dark

Results and discussion

Water solubility
Water solubility:
444 g/L
Temp.:
20 °C
pH:
9.3

Any other information on results incl. tables

The concentration (g/L) of Trisodium [carboxy(oxido)methyl]phosphonate in the sample solution is shown in the following table:

Sample Number Time Shaken at ~ 30C (hours) Time Equilibrated at 20 C (hours) Concentration (g/L) Solution pH
1* 24 24 305.4 9.3
2 48 24 438.9 9.3
3 72 24 448.7 9.3

*considered to have not reached saturation equilibrium and therefore not used in the calculation of the mean water solubility.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The water solubility of the Trisodium [carboxy(oxido)methyl]phosphonate has been determined to be 444 g/L of solution at 20.0 +/- 0.5 C.