Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: study conducted to OECD method with GLP, but used an estimation method

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Principles of method if other than guideline:
Estimation of the partition coefficient was carried out by the visual solubilities in n-octanol and water method, Method A8 of Commission Directive 92/69/EEC (which constitutes Annex V of council directive 67/548/EEC).
GLP compliance:
yes (incl. certificate)
Type of method:
other:
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Hydroxyphosponoaceic acid, trisodium salt (TK13061/2)
- Physical state: Solid (white powder)
- Lot/batch No.: LIC 613/04
- Storage condition of test material: Room temperature in the dark

Results and discussion

Partition coefficientopen allclose all
Type:
log Pow
Partition coefficient:
< -5.65
Temp.:
20 °C
pH:
9.5
Type:
Pow
Partition coefficient:
< 0
Temp.:
20 °C
pH:
9.5

Applicant's summary and conclusion

Conclusions:
The partition coefficient of Trisodium [carboxy(oxido)methyl]phosphonate has been estimated to be less than 2.25E-6, Log Pow <-5.65.