Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 807-821-0 | CAS number: -
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 20-21 February 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Data have been generated according to current internationally recognised study guidelines and in accordance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- GLP compliance:
- yes (incl. QA statement)
- Dissociating properties:
- no
- Conclusions:
- No disccosiation has occured under the conditions of the test.
- Executive summary:
The dissociation constant has been measured in accordance with the OECD 112 test guideline in compliance with GLP. The molecule contains groups which might be expected to dissociate, but under the conditions of the test no dissociation occurs.
Reference
There was no difference between the titration curves of ultrapure water (blank) and the test item solutions. The test item molecule contains dissociable groups, however the dissociation of these groups is very weak (negligible). Dissociation of the test item was not observed in the conditions of this test.
Description of key information
The dissociation constant has been measured in accordance with the OECD 112 test guideline in compliance with GLP. The molecule contains groups which might be expected to dissociate, but under the conditions of the test no dissociation occurs.
Key value for chemical safety assessment
- pKa at 20°C:
- 0
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
