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Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
29 January 2009 to 23 February 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
yes (incl. QA statement)
Remarks:
Date of inspection: 19 August 2008; Date of signature: 29 January 2009
Type of method:
effusion method: vapour pressure balance

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Sponsor's identification : H-CB sodium salt
Description : blue solid
Lot number : MB-2
Date received : 04 December 2008
Storage conditions : room temperature in the dark


Results and discussion

Vapour pressure
Temp.:
25 °C
Vapour pressure:
< 0 Pa
Transition / decomposition
Transition / decomposition:
no

Any other information on results incl. tables

Please see attachment 2 for accompanying graphs.

Run1

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

190

463.15

0.002159128

5.81

5.810E-09

0.008065769

-2.093354246

191

464.15

0.002154476

14.68

1.468E-08

0.020379601

-1.690804323

192

465.15

0.002149844

6.59

6.590E-09

0.009148608

-2.038644964

193

466.15

0.002145232

2.75

2.750E-09

0.003817705

-2.418197685

194

467.15

0.002140640

9.65

9.650E-09

0.013396672

-1.873003065

195

468.15

0.002136067

-0.24

-2.400E-10

-

-

196

469.15

0.002131514

4.32

4.320E-09

0.005997267

-2.222046632

197

470.15

0.002126981

1.26

1.260E-09

0.001749203

-2.757159834

198

471.15

0.002122466

-1.57

-1.570E-09

-

-

199

472.15

0.002117971

0.78

7.800E-10

0.001082840

-2.965435776

200

473.15

0.002113495

-1.26

-1.260E-09

-

-

No statistical analysis is given due to the nature of the plot

Run2

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

190

463.15

0.002159128

-0.24

-2.400E-10

-

-

191

464.15

0.002154476

-0.24

-2.400E-10

-

-

192

465.15

0.002149844

2.20

2.200E-09

0.003054164

-2.515107698

193

466.15

0.002145232

2.59

2.590E-09

0.003595584

-2.444230615

194

467.15

0.002140640

-0.24

-2.400E-10

-

-

195

468.15

0.002136067

3.22

3.220E-09

0.004470185

-2.349674507

196

469.15

0.002131514

3.77

3.770E-09

0.005233726

-2.281189029

197

470.15

0.002126981

-1.10

-1.100E-09

-

-

198

471.15

0.002122466

0.86

8.600E-10

0.001193900

-2.923031927

199

472.15

0.002117971

-0.24

-2.400E-10

-

-

200

473.15

0.002113495

-0.47

-4.700E-10

-

-

 

No statistical analysis is given due to the nature of the plot

Run 3

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

190

463.15

0.002159128

13.82

1.382E-08

0.019185701

-1.717022336

191

464.15

0.002154476

12.79

1.279E-08

0.017755797

-1.750659834

192

465.15

0.002149844

-2.51

-2.510E-09

-

-

193

466.15

0.002145232

1.49

1.490E-09

0.002068502

-2.684344110

194

467.15

0.002140640

0.86

8.600E-10

0.001193900

-2.923031927

195

468.15

0.002136067

-0.78

-7.800E-10

-

-

196

469.15

0.002131514

6.91

6.910E-09

0.009592850

-2.018052331

197

470.15

0.002126981

-0.78

-7.800E-10

-

-

198

471.15

0.002122466

2.59

2.590E-09

0.003595584

-2.444230615

199

472.15

0.002117971

-0.63

-6.300E-10

-

-

200

473.15

0.002113495

0.16

1.600E-10

0.000222121

-3.653410396

No statistical analysis is given due to the nature of the plot

Run 4

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

190

463.15

0.002159128

2.83

2.830E-09

0.003928765

-2.405743943

191

464.15

0.002154476

1.41

1.410E-09

0.001957441

-2.708311266

192

465.15

0.002149844

2.75

2.750E-09

0.003817705

-2.418197685

193

466.15

0.002145232

7.30

7.300E-09

0.010134270

-1.994207519

194

467.15

0.002140640

0.94

9.400E-10

0.001304961

-2.884402525

195

468.15

0.002136067

1.88

1.880E-09

0.002609922

-2.583372529

196

469.15

0.002131514

-0.71

-7.100E-10

-

-

197

470.15

0.002126981

-0.39

-3.900E-10

-

-

198

471.15

0.002122466

2.43

2.430E-09

0.003373463

-2.471924105

199

472.15

0.002117971

0.16

1.600E-10

0.000222121

-3.653410396

200

473.15

0.002113495

-0.55

-5.500E-10

-

-

No statistical analysis is given due to the nature of the plot

Run 5

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapour Pressure (Pa)

Log10Vp

190

463.15

0.002159128

-0.47

-4.700E-10

-

-

191

464.15

0.002154476

0.86

8.600E-10

0.001193900

-2.923031927

192

465.15

0.002149844

-0.55

-5.500E-10

-

-

193

466.15

0.002145232

-0.71

-7.100E-10

-

-

194

467.15

0.002140640

-0.39

-3.900E-10

-

-

195

468.15

0.002136067

-0.24

-2.400E-10

-

-

196

469.15

0.002131514

-1.41

-1.410E-09

-

-

197

470.15

0.002126981

1.18

1.180E-09

0.001638142

-2.785648371

198

471.15

0.002122466

-0.47

-4.700E-10

-

-

199

472.15

0.002117971

0.94

9.400E-10

0.001304961

-2.884402525

200

473.15

0.002113495

1.10

1.100E-09

0.001527082

-2.816137694

No statistical analysis is given due to the nature of the plot

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the test material has been determined to be less than 2.4 x 10-5Pa at 25ºC.
Executive summary:

The vapour pressure was determined using a vapour pressure balance system withasurents being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 Vapour Pressure of Council Regulation (EC) No 440/2008 of 30 May 2008.

The vapour pressure of the test material has been determined to be less than 2.4 x 10-5Pa at 25ºC.