Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 405-800-7 | CAS number: 27955-94-8
Endpoint summary
Administrative data
Description of key information
The test substance was evaluated for the potential for acute skin irritation in rabbit test organisms. There were no signs of irritation at any time during observation.
The test substance was evaluated for the potential for acute eye irritation in the rabbit test organisms. Exposure of the test substance to the rabbit eye produced transient mild conjunctival irritation only fully reversible after 48 hours observation.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Skin Irritation:
The test substance was evaluated for the potential for acute skin irritation in rabbits. A dose of 0.5 g test substance with 0.5 mL water was applied to the intact skin site under a semiocclusive dressing for 4 hours. The application site was then washed and observations made after removal at 30 minutes and Days 2, 3, and 4. There were no signs of irritation at any time point. The test substance was considered to be non-irritant.
Eye Irritation
The test substance was evaluated for acute eye irritation in rabbits. The test substance aliquot was administered to 1 eye of each test organism. The untreated eye served as a control. The conjunctiva, iris, and cornea of each treated eye were evaluated and scored according OECD guideline numerical scale over 7 days. Mild conjunctival inflammation was observed one hour after instillation. All irritation had reversed by 48 hours. No corneal damage or iridial inflammation was observed. The test substance was considered to be non-irritant.
Justification for classification or non-classification
The substance does not meet classification criteria under EU Directive 67/548/EEC for skin irritation.
The substance does not meet classification criteria under Regulation (EC) No 1272/2008 for skin irritation.
The substance does not meet classification criteria under EU Directive 67/548/EEC for eye irritation.
The substance does not meet classification criteria under Regulation (EC) No 1272/2008 for eye irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
