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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

There are two studies available for the oral and dermal acute toxicty of the test substance. The corresponding LD50 were determined as: LD50 (rat) oral >5000 mg/Kg bw. LD50 (rat) dermal >2000 mg/Kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
5 000 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
2 000 mg/kg bw

Additional information

In two separate studies the acute oral and acute dermal toxicity LD50 was determined.

For oral: the test substance suspended in 1% aqueous methylcellulose applied as a single oral dose 5000 mg/kg. The rats were observed for 14 days for mortality and clinical signs. There were no deaths during the observation period and gross necropsy findings were normal. The acute oral LD50 (rat) was >5000 mg/kg bw.

For dermal: The test substance suspended in water was applied with an occlusive dressing at single dose 2000 mg/kg, removed after 24 hours with observation for 14 days. There were no deaths or other clinical signs of toxicity during the observation period. The acute dermal LD50 (rat) was >2000 mg/kg bw.

Justification for classification or non-classification

The substance does not meet classification criteria under EU Directive 67/548/EEC for acute oral toxicity.

The substance does not meet classification criteria under Regulation (EC) No 1272/2008 for acute toxicity.