Registration Dossier
Registration Dossier
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EC number: 903-816-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
The acute oral, dermal and inhalation toxicity of 3-chloropropene, a structural analog to AC Light Ends was evaluated by study protocols similar to current O.E.C.D. Testing Guidelines.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 275 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 3 083 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 070 mg/kg bw
Additional information
The acute oral LD50 of 3 -chloropropene in several rat strains ranged from 275 to 460 mg/Kg of body weight suggesting that 3 -chloropropene is Harmful by the oral route of exposure. The acute dermal LD50 of 3 -chloropropene in rabbits was 2070 mg/Kg of body weight. The 6 hr acute inhalation LC50 of 3 -chloropropene was > 1000 (3083 mg/m3) to < 2000 ppm (6166 mg/m3). These findings are believed to be similar for AC Light Ends.
Justification for classification or non-classification
With an acute oral toxicity LD50 for AC Light Ends in the range of 275 to 460 mg/Kg of body weight Classification and Labeling for acute oral exposure is necessary.
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