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EC number: 208-792-1
CAS number: 541-73-1
No relevant adverse effects on reproductive tissues/organs were detected
at the highest applied dose (588 mg/kg bw/d).
Male and female Sprague-Dawley rats received 1,3-dichlorobenzene daily
doses of 0, 9, 37, 147 or 588 mg/kg bw/day by corn oil gavage for 90
consecutive daily. All rats were observed daily for physiological and
behavioral responses and for mortality. Body weights and food and water
consumption were recorded weekly throughout the study. Blood samples
were collected at necropsy for hematologic and serum chemistriy
measurements prior to necropsy. A gross and histopathological
examination was performed on all major organs inclusive reproductive
organs/tissues (gonads, seminal vesicles, prostate, preputial or
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