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EC number: 700-733-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In this study the test item was found to inhibit the growth of the freshwater green alga Desmodesmus subspicatus after 72 hours. The nominal NOEC-values for inhibition of growth rate and inhibition of yield after 72 hours were 40.0 and 16.0 mg/L, corresponding to geometric mean measured values of 4.40 and 2.20 mg/L, respectively. The nominal LOEC-values for inhibition of growth rate and inhibition of yield after 72 hours were 100 and 40.0 mg/L, corresponding to 15.5 and 4.40 mg/L, respectively. The nominal EC50-values for inhibition of growth rate (ErC50) and yield (EyC50) with 95 % confidence intervals after 72 hours were > 100 and 59.5 (46.5 – 85.2) mg/L, corresponding to > 15.5 and 6.11 (4.90 – 10.4) mg/L, respectively.
All effect levels are given based on nominal and geometric mean measured concentrations of the test item.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 50.5 mg/L
Additional information
The toxicity of the test item to the unicellular freshwater green alga Desmodesmus subspicatus was determined according to the principles of OECD 201.The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours.
The study was conducted under static conditions with an initial cell density of 4910 cells/mL. Based on a preliminary test 5 concentration levels were tested in a geometrical series with a nominal dilution factor of 2.5: 2.56 - 6.40 - 16.0 - 40.0 - 100 mg/L, corresponding to geometric mean measured concentrations of 0.538 – 1.10 – 2.20 – 4.40 – 15.5 mg/L. Three replicates were tested for each test item concentration and six replicates for the control. Environmental conditions were determined to be within the acceptable limits.
The content of aluminium, component of the test item, of the test item concentrations and the control were analytically verified in the fresh media (0 hours, before and after separation phase) and old media (72 hours) with a validated aluminium test (Aluminium Nanocolor – photometric determination with Eriochromcyanin R, Macherey-Nagel). The measured concentration of the stock solution after homogenization was 105 % of the nominal value. After 3 hours of separation of the phases, the supernatant of the stock solution was used for preparation of the test concentrations. The measured concentrations of aluminium in the freshly prepared media were in the range of 14 – 40 % of the nominal value. After 72 hours the measured concentrations were in the range of 9 – 14 % of the nominal values. Details of the analytical method are presented in part 9. The analytical results are presented in Table 8. All effect values given are based on the nominal and the geometric mean measured test item concentrations.
NOEC, LOEC, EC - values and 95 % Confidence Intervals of the test item (0-72 hours)
based on nominal and geometric mean measured test item concentrations [mg/L]
Nominal |
Geometric mean measured |
|
Growth Rate Inhibition |
||
NOEC |
40.0 |
4.40 |
LOEC |
100 |
15.5 |
ErC10 |
50.5 (43.1 – 86.7) |
5.30 (4.64 – 10.8) |
ErC20 |
69.9 (50.5 – 92.9) |
7.14 (5.21 – 12.3) |
ErC50 |
> 100 |
> 15.5 |
Inhibition of Yield |
||
NOEC |
16.0 |
2.20 |
LOEC |
40.0 |
4.40 |
EyC10 |
26.3 (14.5 – 35.6) |
3.21 (2.06 – 4.05) |
EyC20 |
36.2 (22.5 – 67.3) |
4.07 (2.80 – 8.09) |
EyC50 |
59.5 (46.5 – 85.2) |
6.11 (4.90 – 10.4) |
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