Registration Dossier
Registration Dossier
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EC number: 228-711-3 | CAS number: 6334-18-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification
- Justification for type of information:
- QSAR Prediction
Data source
Reference
- Reference Type:
- other: Predicted data
- Title:
- Unnamed
- Year:
- 2 016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,3-dichlorobenzaldehyde
- EC Number:
- 228-711-3
- EC Name:
- 2,3-dichlorobenzaldehyde
- Cas Number:
- 6334-18-5
- Molecular formula:
- C7H4Cl2O
- IUPAC Name:
- 2,3-dichlorobenzaldehyde
- Test material form:
- solid: crystalline
- Details on test material:
- Test item: 2,3-dichlorobenzaldehydeCas No.: 6334-18-5Storage: 15-30 °C
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- primary dermal irritation index (PDII)
- Score:
- 2.88
- Remarks on result:
- other: Database: Skin irritation
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritant) based on GHS criteria
- Conclusions:
- According to (Q)SAR modell: QSAR Toolbox, the predicted value indicated that 2,3-dichlorobenzaldehyde is corrosive to skin. The result meets the requirement of Hazard Category 2.
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