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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

LD50, oral, rat, f ca. > 2000 mg/kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
> 2 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed

Additional information

For the acute toxicity, analogue substances were tested.


For the acute oral toxicity five females of Wistar at limit dose of ca. 2000 mg/kg bw were dosed Under the experimental conditions the LD50, f, > 2000 mg/kg bw. No mortality or signs of toxicity were observed.


 


No deaths or clinical signs related to substance exposure were recorded for the acute dermal toxicity test, with a LC50 > 2000 mg/kg.


Based on the read across considerations same results apply to the target substance.

Justification for classification or non-classification

According to the CLP Regulation (EC n. 1272/2008), table 3.1.1, Acute toxicity hazard categories and acute toxicity estimates (ATE) defining the respective categories:


For Acute toxicity oral route:


Category 1: ATE <= 5 mg/kg bw


Category 2: 5 < ATE <= 50 mg/kg bw


Category 3: 50 < ATE <= 300 mg/kg bw


Category 4: 300 < ATE <= 2000 mg/kg bw


The LD50 of the test substance was determined to be > 2000 mg/kg bw in the chosen reference test, which is outside the limits for classification