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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Prediction by VEGA model is Skin Sensitizer, the result appears reliable. Overall, this information is inconclusive for the classificaztion of the substance.

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
Reference
Endpoint:
skin sensitisation, other
Remarks:
in silico, skin sensitization model
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Qualifier:
according to guideline
Guideline:
other: REACH guidance on QSARs R6, May 2008

Prediction is Sensitizer, the result appears reliable, since: - the predicted compound is into the Applicability Domain of the model - strongly similar compounds with known experimental value in the training set have been found - accuracy of prediction for similar molecules found in the training set is good - similar molecules found in the training set have experimental values that agree with the predicted value - descriptors for this compound have values inside the descriptor range of the compounds of the training set - all atom centered fragment of the compound have been found in the compounds of the training set.

Conclusions:
Prediction is Sensitizer, the result appears reliable. Overall, this information is inconclusive for the classificaztion of the substance.
Endpoint conclusion
Endpoint conclusion:
no study available (further information necessary)

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

No data available.

Justification for classification or non-classification

Data are inconclusive for the classification.