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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a (Q)SAR model, with limited documentation / justification
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
other: Predicted data
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July2008
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
(15α)-3,17-Dioxoandrost-4-en-15-yl acetate
EC Number:
613-793-9
Cas Number:
65429-29-0
Molecular formula:
C21H28O4
IUPAC Name:
(15α)-3,17-Dioxoandrost-4-en-15-yl acetate
Test material form:
solid: crystalline
Details on test material:
Test item: acetoxy-adCas No.: 65429-29-0Batch No.: M64027NStorage: 15-30 °C, protected from light and wet

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
1.36 mg/L
Nominal / measured:
estimated
Remarks on result:
other: Fathead Minnow LC50 96h (EPA)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
1.74 mg/L
Nominal / measured:
estimated
Remarks on result:
other: T.E.S.T. (HCM)

Applicant's summary and conclusion

Conclusions:
According to (Q)SAR modells: VegaNIC, T.E.S.T., the predicted values indicated that acetoxy-ad is hazardous to the fishes. The result meets the requirement of Aquatic Acute Category 2.