Registration Dossier
Registration Dossier
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EC number: 692-120-0 | CAS number: 124955-50-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification
- Justification for type of information:
- QSAR prediction
Data source
Reference
- Reference Type:
- other: Predicted data
- Title:
- Unnamed
- Year:
- 2 015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-(1H-indol-3yl)ethanamine
- EC Number:
- 692-120-0
- Cas Number:
- 124955-50-6
- Molecular formula:
- C10H12N2*H3PO4
- IUPAC Name:
- 2-(1H-indol-3yl)ethanamine
- Test material form:
- solid: crystalline
- Details on test material:
- Test item: tryptamine phosphateCAS No.:124955-50-6Batch No.: S62233NPhysical state: brown or beige crystalline powderStorage: 8-15 °C, protected from light and wet
Constituent 1
Results and discussion
In vivo
Results
- Remarks on result:
- no indication of irritation
- Remarks:
- (based on QSAR/QSPR prediction)
Any other information on results incl. tables
| Software | Method | Alert | Predicted value |
| ChemProp | Skin irritation and corrosion | No Structural Alerts were found. | Save (Not irritating) |
| Toxtree | Skin irritation / skin corrosion | Physical properties | Not Irritating or Corrosive to skin |
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Conclusions:
- According to (Q)SAR modell: Toxtree, ChemProp, the predicted values indicated that tryptamine phosphate is not irritating.
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