Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: other route
Adequacy of study:
other information

Data source

Materials and methods

Administration / exposure

Details on study design:
Test duration 28 days.

Results and discussion

Effect levels

Dose descriptor:
NOAEL
Effect level:
16.4 mg/kg bw/day
Based on:
not specified
Sex:
not specified

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

NONS migrated data summary for 28 day test:

Dose showing no toxic effect: 16.4 mg/kg bw/day.

- No effect dose given or invalid for 28 day test.

- No LIMIT TEST field given for 28 day test.

- No toxic effect dose given or invalid for 90 day test.

- No effect dose given or invalid for 90 day test.

- No LIMIT TEST field given for 90 day test .

Applicant's summary and conclusion

Conclusions:
The repeat dose toxicity based on a 28 day study is reported as showing a NOAEL of 16.4 mg/kg bw/day.