Registration Dossier

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
In silico
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a (Q)SAR model, with limited documentation / justification
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
other: Predicted data
Title:
Unnamed
Year:
2015

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: REACH guidance on QSARs R.6, May/July2008
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline

Results and discussion

In vivo

Results
Remarks on result:
no indication of irritation

Any other information on results incl. tables

Software Method Alert Predicted value
ChemProp Skin irritation and corrosion No Structural Alerts were found. save
Toxtree Skin irritation / skin corrosion No Structural Alerts were found. Not Irritating or Corrosive to skin

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
According to (Q)SAR modells: Toxtree. ChemProp, the predicted values indicated that acetoxy-ad-enolether is not irritating to skin. The result meets the requirement of No Hazard Category.