Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a (Q)SAR model, with limited documentation / justification
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
other: Predicted data
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: REACH guidance on QSARs R.6, May/July2008
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
1.38 mg/L
Nominal / measured:
estimated
Remarks on result:
other: Fathead Minnow LC50 96h (EPA)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
3.32 mg/L
Nominal / measured:
estimated
Remarks on result:
other: Hiearchical Clustering Method (T.E.S.T.)

Applicant's summary and conclusion

Conclusions:
According to (Q)SAR modells: VegaNIC, T.E.S.T., the predicted values indicated that acetoxy-ad-enolether is hazardous to the fishes. The result meets the requirement of Aquatic Acute Category 2.