Registration Dossier

Classification & Labelling & PBT assessment

GHS

General Information

Name:
3-bromophenol
Implementation:
EU
Remarks:

This substance is currently listed on the substances list published by ECHA of those whose met REACH Annex III criteria.

The Annex III inventory is an advisory list, there are not detailed information about the used model and the predictions do not follow OECD principles.

Therefore, the following data can only be used as screening information, but they are not to be considered relevant for the classification and labelling :

# Suspected carcinogen: The Toolbox profiler Carcinogenicity (genotox and nongenotox) alerts by ISS gives an alert for carcinogenicity; ISS Carcinogenicity model in VEGA (Q)SAR platform predicts that the chemical is Carcinogen (moderate reliability)

# Suspected hazardous to the aquatic environment: EPA Daphnia Magna toxicity model in VEGA (Q)SAR platform predicts that the chemical has a 48h EC50 of 2.79 mg/L (good reliability); Fathead Minnow toxicity model (EPA) in VEGA (Q)SAR platform predicts that the chemical has a 96h LC50 of 39.19 mg/L (moderate reliability); Fish toxicity classification (SarPy/IRFMN) model in VEGA (Q)SAR platform predicts that the chemical is Toxic-3 (between 10 and 100 mg/l) (good reliability); Fish Acute Toxicity model (KNN/Read-Across) in VEGA (Q)SAR platform predicts that the chemical has a 96h LC50 of 5.9 mg/L (good reliability);The Danish QSAR database contains information indicating that the substance has a 96h LC50 to fish of 14.85 mg/L; The Danish QSAR database contains information indicating that the substance has a 48h EC50 to Daphnia of 5.35 mg/L; The Danish QSAR database contains information indicating that the substance has a 96h EC50 to green algae of 23.66 mg/L

# Suspected mutagen: The Toolbox profiler Protein binding alerts for Chromosomal aberration by OASIS v1.1 gives an alert for mutagenicity

# Suspected persistent in the environment: The Danish QSAR database contains information indicating that the substance is predicted as non readily biodegradable

# Suspected skin irritant: The Danish QSAR database contains information indicating that the substance is predicted as skin irritant

Classificationopen allclose all

Explosives
Reason for no classification:
data lacking
Flammable gases and chemically unstable gases
Reason for no classification:
data conclusive but not sufficient for classification
Aerosols
Reason for no classification:
data conclusive but not sufficient for classification
Oxidising gases
Reason for no classification:
data conclusive but not sufficient for classification
Gases under pressure
Reason for no classification:
data conclusive but not sufficient for classification
Flammable liquids
Reason for no classification:
data conclusive but not sufficient for classification
Flammable solids
Reason for no classification:
data lacking
Self-reactive substances and mixtures
Reason for no classification:
data lacking
Pyrophoric liquids
Reason for no classification:
data conclusive but not sufficient for classification
Pyrophoric solids
Reason for no classification:
data lacking
Self-heating substances and mixtures
Reason for no classification:
data lacking
Substances and mixtures which in contact with water emit flammable gases
Reason for no classification:
data lacking
Oxidising liquids
Reason for no classification:
data conclusive but not sufficient for classification
Oxidising solids
Reason for no classification:
data lacking
Organic peroxides
Reason for no classification:
data conclusive but not sufficient for classification
Corrosive to metals
Reason for no classification:
data lacking
Desensitized explosives
Reason for no classification:
data lacking
Acute toxicity - oral
Reason for no classification:
data lacking
Acute toxicity - dermal
Reason for no classification:
data lacking
Acute toxicity - inhalation
Reason for no classification:
data lacking
Skin corrosion / irritation
Hazard category:
Skin Irrit. 2
Hazard statement:
H315: Causes skin irritation.
Serious eye damage / eye irritation
Hazard category:
Eye Irrit. 2
Hazard statement:
H319: Causes serious eye irritation.
Respiratory sensitisation
Reason for no classification:
data lacking
Skin sensitisation
Reason for no classification:
data lacking
Aspiration hazard
Reason for no classification:
data lacking
Reproductive toxicity
Reason for no classification:
data lacking
Effects on or via lactation
Reason for no classification:
data lacking
Germ cell mutagenicity
Reason for no classification:
data lacking
Carcinogenicity
Reason for no classification:
data lacking
1. Specific target organ toxicity - single
Hazard category:
STOT Single Exp. 3
Hazard statement:
H335: May cause respiratory irritation.
Affected organs:
high respiratory tract
1. Specific target organ toxicity - repeated
Reason for no classification:
data lacking
Hazardous to the aquatic environment (acute / short-term)
Reason for no classification:
data lacking
Hazardous to the aquatic environment (long-term)
Reason for no classification:
data lacking
Hazardous to the ozone layer
Reason for no classification:
data lacking

Labelling

Signal word:
Warning

Hazard pictogram

GHS07: exclamation mark

Hazard statements

H319: Causes serious eye irritation.
H315: Causes skin irritation.
H335: May cause respiratory irritation.

Precautionary statements

P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.

Notes