Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Study period:
not applicable
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The data reported are those from the analogue substance "Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda" (for justification of read-across between the registered substance and its analogue, please refer to corresponding assessment report in Section 13).

Data source

Materials and methods

Test material

Constituent 1
Reference substance name:
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda
EC Number:
939-368-0
Molecular formula:
Not applicable (a generic molecular formula can not be provided for this specific UVCB substance)
IUPAC Name:
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Results:
Case of irritant effects of the respiratory tract were reported in workers when powder of Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda is manipulated in the manufacturing plant. Owing to its structure similarity, Reaction product of naphthalene, butanol, sulfonated and neutralized by caustic soda is expected to display comparable effects when handled it its powder form.

Applicant's summary and conclusion

Executive summary:

Case of irritant effects of the respiratory tract were reported in workers when powder of Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda is manipulated in the manufacturing plant. Owing to its structure similarity, Reaction product of naphthalene, butanol, sulfonated and neutralized by caustic soda is expected to display comparable effects when handled it its powder form.