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EC number: 239-362-1
CAS number: 15332-99-7
Tris(isopropenyloxy)(vinyl)silane has been tested for acute oral
toxicity according to OECD 401 (TNO, 1983); there is no information on
GLP compliance. The following clinical signs were observed after ten
male and ten female Wistar rats were dosed with 20 ml/kg bw:
sluggishness, ataxia and rough coats. A single male died on the second
day. It is concluded that the LD50 is >20 ml/kg bw, which is
equivalent to approximately 18000 mg/kg, based on a density of 0.9 g/cm3.
Tris(isopropenyloxy)(vinyl)silane has been tested for acute inhalation
(aerosol) toxicity in rats in a study conducted according to OECD 403
and in compliance with GLP (RCC, 1989). No mortalities occurred, and
treatment-related effects were confined to piloerection and apathy on
the day after administration, in the five male and five female rats
treated with an aerosol containing 4.31 mg/l of the test substance. It
is concluded that the LD50 is >4.31 mg/l under the conditions
of the test.
Based on the available studies on acute toxicity,
tris(isopropenyloxy)(vinyl)silane does not require classification
according to Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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