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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 17, 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Principles of method if other than guideline:
Laser light scattering. The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure the size of particles. It does this by measuring the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
ca. 33.564 µm
Remarks on result:
other: After 2 minutes of ultrasonic treatment
Percentile:
D10
Mean:
ca. 10.748 µm
Remarks on result:
other: After 2 minutes of ultrasonic treatment
Percentile:
D90
Mean:
ca. 78.228 µm
Remarks on result:
other: After 2 minutes of ultrasonic treatment

The analysis was conducted after 2 minutes of sample sonification.

Conclusions:
D10= 10.748 µm
D50= 33.564 µm
D90= 78.228 µm
Executive summary:

Method

The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure the size of particles. It does this by measuring the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.

Result

Analysis carried out after 2 minutes of ultrasonic treatment:

D10=10.748 µm

D50=33.564 µm

D90=78.228 µm

Description of key information

Median Mass Diameter = 33.564 µm

Additional information

Laser light scattering method.