Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

Contact sensitivity to aluminium is very rare. Several review articles report a low incidence of hypersensitization of aluminium compounds even after subcutaneous and intramuscular injections. The risk of hypersensitization after dermal application of a poorly soluble compound like aluminium nitride is considered to be lower compared to subcutaneous injection. Therefore, conducting a vertebrate test with aluminium nitride is considered to be scientifically unjustified and would not respect animal welfare considerations.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Contact sensitivity to aluminium is very rare. Several review articles report a low incidence of hypersensitization of aluminium compounds even after subcutaneous and intramuscular injections. The risk of hypersensitization after dermal application of a poorly soluble compound like aluminium nitride is considered to be lower compared to subcutaneous injection. Therefore, conducting a vertebrate test with aluminium nitride is considered to be scientifically unjustified and would not respect animal welfare considerations.