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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The effect concentration (EC50) value of biphenyl-2-ylamine fish (Brachydanio rerio (new name: Danio rerio)) in a 96 hr study on mortality effect was found to be 94.197181702 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
94.197 mg/L

Additional information

Weight of evidence studies including the predicted data for target chemical data reviewed for short-term toxicity to fish from reliable sources having Klimish rating 2.

The summary of the results are presented below:

Sr. No

Endpoint

Value

Duration

Species

Sources

1.

LC50

94.197181702 mg/L

96 hr

Brachydanio rerio (new name: Danio rerio)

QSAR Predicted data

2.

LC0

5 mg/L.

24 hr

almo gairdneri (new name: Oncorhynchus mykiss)

Data from study report

3..

LC0

5 mg/L.

24 hr

Lepomis macrochirus

Data from study report

 

Thus considering the above predicted value for target chemical was 94.197181702 mg/l and from other study data available is 5 mg/L in 24 Hr. Thus as per the CLP criteria for aquatic classification of the substance it is concluded that biphenyl-2-ylamine would exhibit short term toxicity in the fish in Aquatic Chronic 3 category (which is the harmonized CLP classification).