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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The effect concentration (EC50) value of biphenyl-2-ylamine fish (Brachydanio rerio (new name: Danio rerio)) in a 96 hr study on mortality effect was found to be 94.197181702 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
94.197 mg/L

Additional information

Weight of evidence studies including the predicted data for target chemical data reviewed for short-term toxicity to fish from reliable sources having Klimish rating 2.

The summary of the results are presented below:

Sr. No








94.197181702 mg/L

96 hr

Brachydanio rerio (new name: Danio rerio)

QSAR Predicted data



5 mg/L.

24 hr

almo gairdneri (new name: Oncorhynchus mykiss)

Data from study report



5 mg/L.

24 hr

Lepomis macrochirus

Data from study report


Thus considering the above predicted value for target chemical was 94.197181702 mg/l and from other study data available is 5 mg/L in 24 Hr. Thus as per the CLP criteria for aquatic classification of the substance it is concluded that biphenyl-2-ylamine would exhibit short term toxicity in the fish in Aquatic Chronic 3 category (which is the harmonized CLP classification).