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EC number: 248-702-8 | CAS number: 27870-92-4
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species, other
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: data from modelling database
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: predicted data
- Principles of method if other than guideline:
- BCFBAF Program (v3.01)
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
estimated data - Radiolabelling:
- not specified
- Details on sampling:
- estimated data
- Vehicle:
- not specified
- Details on preparation of test solutions, spiked fish food or sediment:
- estimated data
- Test organisms (species):
- other: fish
- Details on test organisms:
- estimated data
- Route of exposure:
- aqueous
- Test type:
- static
- Water / sediment media type:
- not specified
- Remarks:
- freshwater
- pH:
- estimated data
- Dissolved oxygen:
- estimated data
- TOC:
- estimated data
- Salinity:
- estimated data
- Details on test conditions:
- estimated data
- Nominal and measured concentrations:
- estimated data
- Type:
- BCF
- Value:
- 18.09 L/kg
- Basis:
- other: estimated data
- Calculation basis:
- other: estimated data
- Remarks on result:
- other: Log BCF (regression-based estimate): 1.257 (BCF = 18.09 L/kg wet-wt)
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The estimated BCF value for 2 Octadecyl1Hthioxantheno(2,1,9def)isoquinoline1,3(2H)dione in fish was 18.09 L/kg
- Executive summary:
Bioaccumulation potential of2 Octadecyl-1H-thioxantheno(2,1,9-def)isoquinoline-1,3(2H)-dione was estimated by BCFBAF v3.01 Program from EPISuite Version 4.1.
BCFBAF v3.01
Log BCF (regression-based estimate): 1.26 (BCF = 18.1 L/kg wet-wt)
Biotransformation Half-Life (days) : 162 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): 2.01 (BAF = 101 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: 12.85
Equation Used to Make BCF estimate:
Log BCF = -0.49 log Kow + 7.554 + Correction
Correction(s): Value
No Applicable Correction Factors
Estimated Log BCF = 1.257 (BCF = 18.09 L/kg wet-wt)
The estimated BCF value for 2 Octadecyl-1H-thioxantheno (2,1,9-def)isoquinoline-1,3(2H)-dione in fish was 18.09 L/kg
Based on the classification criterion for PBT,2 Octadecyl -1H-thioxantheno (2,1,9-def)isoquinoline-1,3(2H)-dione can be considered to be non- bioaccumulative in nature.
Reference
BCFBAF v3.01
Log BCF (regression-based estimate): 1.26 (BCF = 18.1 L/kg wet-wt)
Biotransformation Half-Life (days) : 162 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): 2.01 (BAF = 101 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: 12.85
Equation Used to Make BCF estimate:
Log BCF = -0.49 log Kow + 7.554 + Correction
Correction(s): Value
No Applicable Correction Factors
Estimated Log BCF = 1.257 (BCF = 18.09 L/kg wet-wt)Description of key information
The estimated BCF value for 2 Octadecyl1Hthioxantheno(2,1,9def)isoquinoline1,3(2H)dione in fish was 18.09 L/kg
Key value for chemical safety assessment
- BCF (aquatic species):
- 18.09 L/kg ww
Additional information
Bioaccumulation potential of 2 Octadecyl-1H-thioxantheno(2,1,9-def)isoquinoline-1,3(2H)-dione was estimated by BCFBAF v3.01 Program from EPISuite Version 4.11. The estimated BCF value for 2 Octadecyl-1H-thioxantheno (2,1,9-def)isoquinoline-1,3(2H)-dione in fish was 18.09 L/kg .
Based on the classification criterion for PBT, 2 Octadecyl -1H-thioxantheno (2,1,9-def)isoquinoline-1,3(2H)-dione can be considered to be non- bioaccumulative in nature.
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