Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-992-5 | CAS number: 7783-35-9
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: invertebrate
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from peer reviewed journal
Data source
Reference
- Reference Type:
- publication
- Title:
- Influence of glyphosate and its formulation (Roundup) on the toxicity and bioavailability of metals to Ceriodaphnia dubia
- Author:
- Martin T.K. Tsui, Wen-Xiong Wang , L.M. Chu ,
- Year:
- 2 005
- Bibliographic source:
- Environmental Pollution 138 (2005) 59-68
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- Data is from peer reviewed journal
- GLP compliance:
- no
Test material
- Reference substance name:
- Mercury sulphate
- EC Number:
- 231-992-5
- EC Name:
- Mercury sulphate
- Cas Number:
- 7783-35-9
- Molecular formula:
- H2O4S.Hg
- IUPAC Name:
- mercury sulfate
- Reference substance name:
- Sulfuric acid, Mercury(2+) salt(1:1)
- IUPAC Name:
- Sulfuric acid, Mercury(2+) salt(1:1)
- Details on test material:
- - Name of test material: Mercury sulphate
- Molecular formula: H2O4S.Hg
- Molecular weight : 298.67 g/mol
- Smiles notation: [O-]S(=O)(=O)[O-].[Hg+2]
- InChl : InChI=1S/Hg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
- Substance type: Solid
- Physical state: Inorganic
- Impurities (identity and concentrations): No data
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No data available - Radiolabelling:
- yes
Sampling and analysis
- Details on sampling:
- No data available
Test solutions
- Vehicle:
- not specified
- Details on preparation of test solutions, spiked fish food or sediment:
- Details on preparation of test solutions or sediment (aquatic)
PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: No data available
- Controls: Yes
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): No data available
- Concentration of vehicle in test medium (stock solution and final test solution(s) at different concentrations and in control(s)): No data available
- Evidence of undissolved material (e.g. precipitate, surface film, etc): No data available
Test organisms
- Test organisms (species):
- Ceriodaphnia dubia
- Details on test organisms:
- Details on test organisms
TEST ORGANISM
- Common name: Water flea
- Strain: No data available
- Source: Aquatic Research Organisms (Hampton, NH, USA)
- Age at study initiation (mean and range, SD): Adults Ceriodaphnia dubia
- Weight at study initiation (mean and range, SD): No data available
- Length at study initiation (length definition, mean, range and SD): No data available
- Valve height at study initiation, for shell deposition study (mean and range, SD): No data available
- Peripheral shell growth removed prior to test initiation: No data available
- Method of breeding: No data available
- Feeding during test: No data available
- Food type: Selenastrum capricornutum and yeastecerophyle
trout chow
- Amount: No data available
- Frequency: 2
ACCLIMATION
- Acclimation period: No data available
- Acclimation conditions (same as test or not): No data available
- Type and amount of food:
- Feeding frequency: No data available
- Health during acclimation (any mortality observed): No data available
QUARANTINE (wild caught)
- Duration: No data available
- Health/mortality: No data available
Study design
- Route of exposure:
- aqueous
- Test type:
- not specified
- Water / sediment media type:
- not specified
- Total exposure / uptake duration:
- 4 h
Test conditions
- Hardness:
- No data available
- Test temperature:
- No data available
- pH:
- No data available
- Dissolved oxygen:
- No data available
- TOC:
- No data available
- Salinity:
- No data available
- Details on test conditions:
- Details on test conditions
TEST SYSTEM
- Test vessel: polypropylene beaker
- Type (delete if not applicable): open
- Material, size, headspace, fill volume: 100ml
- Aeration: No data available
- Type of flow-through (e.g. peristaltic or proportional diluter): No data available
- Renewal rate of test solution (frequency/flow rate): No data available
- No. of organisms per vessel: 10 to 20
individuals
- No. of vessels per concentration (replicates): No data available
- No. of vessels per control / vehicle control (replicates): No data available
- Biomass loading rate: No data available
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: No data available
- Particulate matter: No data available
- Metals: No data available
- Pesticides: No data available
- Chlorine: No data available
- Alkalinity: No data available
- Ca/mg ratio: No data available
- Conductance: No data available
- Holding medium different from test medium: No data available
- Intervals of water quality measurement: No data available
- Intervals of test medium replacement: No data available
OTHER TEST CONDITIONS
- Adjustment of pH: 25°C
- Photoperiod: No data available
- Light intensity: No data available
RANGE-FINDING / PRELIMINARY STUDY
- Test concentrations: No data available
- Results used to determine the conditions for the definitive study: No data available - Nominal and measured concentrations:
- Nominal: 5000, 10000, 15000, 20000 L kg-1)
- Reference substance (positive control):
- not specified
- Details on estimation of bioconcentration:
- No data available
Results and discussion
Bioaccumulation factor
- Type:
- other: No data available
- Value:
- > 0 - < 5 000
- Basis:
- other: Bioconcentration
- Remarks on result:
- other: Conc.in environment / dose:No data available
- Details on kinetic parameters:
- No data available
- Metabolites:
- No data available
- Results with reference substance (positive control):
- No data available
- Details on results:
- No data available
- Reported statistics:
- No data available
Applicant's summary and conclusion
- Conclusions:
- The bioconcentration value for the Ceriodaphnia dubia was found to be (> 0 to < 5000) value when treated with Sulfuric acid, Mercury (2+) salt (1:1) (7783-35-9).
- Executive summary:
The bioconcentration test was performed on Ceriodaphnia dubia when treated with Mercury (2+) salt (1:1). Adults were used and two treatments were given as glyphosate was mixed with203Hg (0.71 nM) in the
diluent water for 30 min in a polypropylene beaker. Another only metal solution was stir for 30 minutes. After 4 hours of exposure Ceriodaphnia dubia were collected and check for radioactivity.
From the above experiment it was found that the bioconcentration value for the Ceriodaphnia dubia was found to be (> 0 to < 5000) value when treated with Sulfuric acid, Mercury (2+) salt (1:1) (7783-35-9).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
