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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Readily biodegradable: 63% after 28 d (CO2 evolution, OECD 310)

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

One experimental study is available investigating the ready biodegradability of the test substance (Fiebig, 2011). The study was performed according to OECD 310 (GLP). Activated sludge from a domestic sewage treatment plant was used as inoculum. 63% degradation of the test substance was recorded based on CO2 evolution after 28 d. The 10-day window was not met. However, since the substance is a multi-constituent substance and consists of structurally similar constituents (in this case: stereo-isomers), sequential (instead of concurrent) biodegradation of the individual structures can take place, but all can be considered as readily biodegradable. Thus, referring to the OECD Guideline for Testing of Chemicals ‘Revised introduction to the OECD guidelines for testing of chemicals, section 3’ (OECD, March 2006) and ECHA Guidance R.7b (ECHA, 2016), the 10-day window should not be considered for this multi-constituent substance and due to a degradation of >60 % within 28 days the substance can be regarded as readily biodegradable. A toxicity control containing both, reference substance and test substance, did not indicate inhibitory effects of the test substance to the inoculum (55% degradation after 14 d; trigger value of 25% biodegradation in the toxicity control was reached).