Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Partition Coefficient- Octanol – Water
Author:
Philip J Howard
Year:
2016
Bibliographic source:
Handbook of Physical Properties of Organic Chemicals, 1st Edition
Reference Type:
review article or handbook
Title:
Partition Coefficient- Octanol – Water
Author:
SRC Physprop database
Year:
2012
Bibliographic source:
SRC (Syracuse Research Corporation) PhysProp Database;
Reference Type:
review article or handbook
Title:
Partition Coefficient- Octanol – Water
Author:
Emanuele Argese, Cinzia Bettiol, Matteo Fasolo, Alfonso Zambon, Francesca Agnoli
Year:
2002
Bibliographic source:
Biochimica et Biophysica Acta 1558 (2002) 151-160

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Partition coefficient of chemical 3'-aminoacetophenone was determined.
GLP compliance:
no
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material: 3’-aminoacetophenone
- Molecular formula: C8H9NO
- Molecular weight: 135.16 g/mol
- Substance type: Organic
- Physical state: Liquid

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
0.83
Remarks on result:
other: Other details not known

Applicant's summary and conclusion

Conclusions:
The experimental value of Log Pow is 0.83
Executive summary:

The experimental value of Log Powis 0.83