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Partition coefficient

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Description of key information

- Log Kow for alcohols in vetivert oil: 4.1 - 5.63
- Log Kow for hydrocarbons in vetivert: 5.74 - 6.32
- Log Kow for ketones in vetivert oil: 3.35 - 4.93

Key value for chemical safety assessment

Additional information

Vetivert oil is a NCS consisting of > 140 constituents. For 24 of the major constituents, divided over 3 different functional groups (alcohols, hydrocarbons and ketones), log Kow values have been estimated using the EPISUITE 3.20 Kowwin (Q)SAR. These 24 constituents make up 70.6% of the total composition of vetivert oil. The functional groups, the number of constituents in each group, the percentage of the functional group in the total composition of vetivert oil and the log Kow range for each group are reported below.

Alcohols (n=10, 47.1%): 4.1 - 5.63

Hydrocarbons (n=9, 11.8%): 5.74 - 6.32

Ketones (n=5, 11.7%): 3.35 - 4.93

Based on these estimations it can be concluded that >25% w/w of vetivert oil has a log Kow >4 (as alcohols are the main component). This leads to a R53 classification under the classification criteria of 67/548/EC and may lead to a classification as chronicically ecotoxic under 1272/2008/EC, dependent on substance ecotoxicity.

This result should be used for classification and risk assessment.