Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Bioaccumulation: aquatic/sediment

An experimental study was conducted on fish for determining the BCF (bioaccumulation factor) value of test chemical Trichloroacetaldehyde (CAS no. 75-87-6) (HSDB, 2016). The BCF (bioaccumulation factor) was calculated using a log Kow of 1.2 and a regression-derived equation. The BCF (bioaccumulation factor) of test chemical Trichloroacetaldehyde was determined to be 5 which does not exceed the bioconcentration threshold of 2000, indicating that the chemical Trichloroacetaldehyde is considered to be non-accumulative in aquatic organisms.

Additional information

Bioaccumulation: aquatic/sediment

Various experimental study and predicted data for the target compound Trichloroacetaldehyde (CAS No. 75-87-6) were reviewed for the bioaccumulation end point which are summarized as below:

 

In an experimental key study from authoritative database (HSDB, 2016), study was conducted on fish for determining the BCF (bioaccumulation factor) value of test chemical Trichloroacetaldehyde (CAS no. 75-87-6). The BCF (bioaccumulation factor) was calculated using a log Kow of 1.2 and a regression-derived equation. The BCF (bioaccumulation factor) of test chemical Trichloroacetaldehyde was determined to be 5.

 

In a supporting study, experiment was conducted for determining the BCF (bioaccumulation factor) value of test chemical Trichloroacetaldehyde (CAS no. 75-87-6) (SRC (Syracuse Research Corporation) PhysProp Database, 2017). The BCF (bioaccumulation factor) of test chemical Trichloroacetaldehyde was determined to be 3.326 (Log BCF = 0.522).

 

For target chemical Trichloroacetaldehyde(CAS No. 75-87-6), the bioconcentration factor (BCF) of test chemical Trichloroacetaldehyde (CAS no. 75-87-6) was predicted using the BCFBAF Program (v3.01) of Estimation Programs Interface (EPI Suite, 2017). The estimated bioconcentration factor (BCF) of Trichloroacetaldehyde was 3.162 L/kg whole body w.w (at 25 deg C).

 

In an another prediction done by using Bio-concentration Factor (v12.1.0.50374) module, the BCF (ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017) over the entire pH scale (pH 0 - 14) of the test substance Trichloroacetaldehyde(CAS No. 75-87-6)was estimated to be 9.85 (log BCF = 1.0 ± 1.0). This value indicates that the test substance Trichloroacetaldehyde was considered to be non-accumulative in aquatic organisms.

 

On the basis of above results for target chemicalTrichloroacetaldehyde (from authoritative database HSDB, SRC PhysProp Database, EPI suite and ACD labs), it can be concluded that the BCF value of test substance Trichloroacetaldehyde ranges from 3.162 – 9.85 which does not exceed the bioconcentration threshold of 2000, indicating that the chemical is not expected to bioaccumulate in the food chain.