Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Regulatory accepted QSAR method for organic chemicals properties assessment.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: QSAR method
Principles of method if other than guideline:
QSAR method:ECOSAR Program (v1.00)
GLP compliance:
no
Remarks:
not applicable to QSAR models

Test material

Constituent 1
Chemical structure
Reference substance name:
Styrene
EC Number:
202-851-5
EC Name:
Styrene
Cas Number:
100-42-5
Molecular formula:
C8H8
IUPAC Name:
ethenylbenzene

Results and discussion

Any other information on results incl. tables

Sublethal observations / clinical signs:

Overview of QSARs estimations on short-term aquatic toxicity of styrene to fish

Method

 

Results

Remarks

Reference

QSAR

estimate

LC50 (96-hour, fish) =13.094 mg/L (ppm);

 

LC50 (96-hour, fish SW) =17.007 mg/L (ppm)

Reliable with

restrictions,

QSAR estimated

data

ECOSAR

Program

(v1.00)

Applicant's summary and conclusion

Conclusions:
The QSAR estimated data on acute aquatic toxicity of styrene to fish is summarised as follows:
LC50 (96-hour, fish) =13.094 mg/L (ppm);
LC50 (96-hour, fish SW) =17.007 mg/L (ppm)