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Registration Dossier
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EC number: 254-184-4 | CAS number: 38900-29-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The activated sludge respiration inhibition test does not need to be conducted as the substances in the lithium salts of dicarboxylic acids (C6 - C10) category are readily biodegradable at concentrations that may be expected in the influent of a sewage treatment plant.
Key value for chemical safety assessment
Additional information
The activated sludge respiration inhibition test does not need to be conducted as the substances in the lithium salts of dicarboxylic acids (C6 - C10) category are readily biodegradable at concentrations that may be expected in the influent of a sewage treatment plant. The substances would dissociate and biodegrade in the environment, resulting in carbon dioxide, water and lithium ions.
Biodegradation data are available for the organic components. In the biodegradation studies (Gerike and Fischer 1979), adipic acid was readily biodegradable at all concentrations tested (up to 50 mg/L DOC, equivalent to 109.6 mg/L dilithium adipate) and was inherently biodegradable at 400 mg/L DOC (equivalent to 877 mg/L dilithium adipate). Although no toxicity controls were undertaken in the studies, as adipic acid meets the criteria for ready biodegradability, it is not considered toxic to micro-organisms. This conclusion is read across to other members of the category.
The lithium ion is inorganic and therefore ready biodegradability is not relevant. Lithium has an EC50 of 52.29 mg/L and an EC10 of 22.95 mg/L for toxicity to aquatic micro-organisms (ECHA Dissemination Portal). This would equate to an EC10 of 260.8 mg/L for dilithium adipate, which is above the NOEC calculated from the adipic acid result, indicating that the lithium component would not drive any toxicity to micro-organisms.
This is supported by the ready biodegradability result for dilithium glutarate (C5 – see dissemination portal) which shows that the presence of the lithium ion is not expected to impact the degradation of the dilithium salts. Further testing on the ready biodegradability of dilithium sebacate is currently ongoing to confirm this conclusion.
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