Alcohols, C12-14

Endpoint summary

Additional information

Biodegradation

Biodegradation in water:screening tests

 

Data of following studies are demonstrating rapid biodegradation Alcohols, C12-14 under aerobic conditions.

 

 Henkel KGaA. , 1997 conducted BOD-test for Insoluble Substances (BODIS); ISO 10708 for Biodegradation of Alcohols, C12-14.

 

The test method used is based on OECD test method 301D and the RDA-Blok-Test. Mineral medium was inoculated with activated sludge and stabilized for one week at 18-22 C with continuous stirring. After stabilisation, 200 ml of test medium was filled into 300 ml bottles, aerated until O2 saturation was reached and spiked with test substance by directly weighing into the test vessels.

Degradation was 79 - 97 % after 28 day(s), the substance is considered to be readily biodegradable

 

The BIOWIN QSAR predicts that the substance Alcohols, C12-14 will be readily biodegradable.

 

Richterich , 1993 conducted OECD 301D test for Biodegradation of Alcohols, C12 (1-Dodecanol). Degradation was 79 % after 28 day(s) , the substance is considered to be readily biodegradable. Dodecan-1-ol (C12) is supporting substance for Alcohols, C12-C14 and the main component. The test substance (2 mg/l) attained >60% degradation during the 14 day window.

 

Henkel KGaA. , 1992 conducted OECD test method 301D and BOD-test for Insoluble Substances (BODIS); ISO 10708 for Biodegradation of Dodecan-1-ol (C12. Degradation was 100 % after 28 day(s) , the substance is considered to be readily biodegradable.

The substance degraded >60% in the 10 day window. .Dodecan-1-ol (C12) is supporting substance for Alcohols, C12-C14 and the main component.

Morris, P.A., Filler, P.A., and Nielsen, A.M. (1991) conducted OECD 301B test and Degradationwas 71 % after 28 day(s) , the substance is considered to be readily biodegradable. The substance degraded >60% in the 14 day window. .Dodecan-1-ol (C12) is supporting substance for Alcohols,C12-C14 and the main component. The reference substance Sodium acetate degraded by 78% after 28 days.

 

 

 

Table     Summary of Biodegradation in water:screening tests

 

Type/ Method	Test material	Degradation	Duration	References
Aerobic/ OECD 301D/(BODIS)	Alcohols, C12-14	79-97% in 28 days at 100 mg/L	28 days	Henkel KGaA. , 1997
Aerobic/ OECD 301D	Alcohols, C12 (1-Dodecanol).	79%	28 days	Richterich , 1993
Aerobic/ OECD 301D/(BODIS	Alcohols, C12 (1-Dodecanol).	100 %	28 days	Henkel KGaA. , 1992
Aerobic/ OECD 301D	Alcohols, C12 (1-Dodecanol).	71 %	28 days	Morris, P.A., Filler, P.A., and Nielsen, A.M. (1991)

 

 

 

Biodegradation in water and sediment: simulation tests

 

According to “ANNEX IX- STANDARD INFORMATION REQUIREMENTS FOR SUBSTANCES MANUFACTURED OR IMPORTED IN QUANTITIES OF 100 TONNES OR MORE”, a simulation testing on ultimate degradation in surface water, the study does not need to be performed if the substance is ready biodegradable. As Alcohols, C12-14 is ready biodegradable a ready biodegradability study does not need to be conducted.

Therefore testing for Biodegradation in water does not need to be performed 

Biodegradation in soil

 

Expert Judgement

 If released to soil, Alcohols, C12-14 is expected to have very high mobility based upon an estimated Koc of 2245. Volatilization from moist soil surfaces is not expected to be an important fate process.      

 Therefore testing for Biodegradation in water does not need to be performed