Registration Dossier
Registration Dossier
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EC number: 208-523-8 | CAS number: 532-02-5
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Short term toxicity to fish by ECOSAR Version 1.10
- Author:
- ECOSAR Version 1.10
- Year:
- 2 016
- Bibliographic source:
- ECOSAR v1.1 Class-specific Estimations, Environmental Protection Agency (EPA) office of Chemical Safety and Pollution Prevention
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modeling database
- Principles of method if other than guideline:
- ECOSAR v1.00
- GLP compliance:
- no
Test material
- Reference substance name:
- Sodium naphthalene-2-sulphonate
- EC Number:
- 208-523-8
- EC Name:
- Sodium naphthalene-2-sulphonate
- Cas Number:
- 532-02-5
- Molecular formula:
- C10H8O3S.Na
- IUPAC Name:
- sodium naphthalene-2-sulphonate
- Details on test material:
- - Name of test material (as cited in study report): Sodium naphthalene-2-sulphonate
- Substance type: Organic
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- other: Fish
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 105 000 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Chemical may not be soluble enough
Applicant's summary and conclusion
- Conclusions:
- Based on the QSAR prediction done using the EPI Suite ECOSAR version 1.10, the 96 hours LC50 was estimated to be 105000 mg/L on fish for substance Sodium naphthalene-2-sulphonate with mortality effects. Thus based on this value it can be concluded that the substance can be classified as non hazardous as per the criteria of CLP regulation.
- Executive summary:
Based on the QSAR prediction done using the EPI Suite ECOSAR version 1.10, the 96 hours LC50 was estimated to be 105000 mg/L on fish for substance Sodium naphthalene-2-sulphonate with mortality effects. Thus based on this value it can be concluded that the substance can be classified as non hazardous as per the criteria of CLP regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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