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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to microorganisms, other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Qualifier:
according to guideline
Guideline:
other: Refer below principle
Principles of method if other than guideline:
Toxicity to micro organism Microregma sp.(Ciliated Protozoa) was determine for chemical Methylamine hydrochloride.
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material (as cited in study report): Methylamine hydrochloride
- Molecular formula (if other than submission substance): CH5N.Cl H
- Molecular weight (if other than submission substance): 67.5184 g/mol
- Smiles notation (if other than submission substance): C[NH3+].[ClH-]
- InChl (if other than submission substance): 1S/CH5N.ClH/c1-2;/h2H2,1H3;1H
- Substance type: Organic
- Physical state: Solid
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
other: Microregma sp.(Ciliated Protozoa)
Details on inoculum:
Strain: MICROREGMA HETEROSTOMA
-Age :48 h
Test type:
static
Water media type:
freshwater
Total exposure duration:
28 h
Hardness:
12 dH
Test temperature:
27 deg.C
pH:
7.5 to 7.8
Dissolved oxygen:
No data
Salinity:
ALKALINITY: 3 ml N/100 HCl
Conductivity:
No data
Reference substance (positive control):
not specified
Key result
Duration:
28 h
Dose descriptor:
EC50
Effect conc.:
50 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: Feeding behavior
Validity criteria fulfilled:
not specified
Conclusions:
Experimental result suggests the effect concentration (EC50) for the substance Methylamine hydrochloride (CAS no. 593-51-1) was determine to be 50 mgl/L on micro organism species Microregma sp. (Ciliated Protozoa) on the basis of effect on Feeding behavior in static fresh water.
Executive summary:

Experimental result suggests the effect concentration (EC50) for the substance Methylamine hydrochloride (CAS no. 593-51-1) was determine to be 50 mgl/L on micro organism species Microregma sp.(Ciliated Protozoa) on the basis of effect on Feeding behavior in static fresh water.

Thus based on the observed effects it is concluded that the chemical Methylamine hydrochloride (CAS no. 593-51-1) may have toxicity concern to micro organism for acute exposure period.

Description of key information

Experimental result suggests the effect concentration (EC50) for the substance Methylamine hydrochloride (CAS no. 593-51-1) was determine to be 50 mgl/L on micro organism species Microregma sp. (Ciliated Protozoa) on the basis of effect on Feeding behavior in static fresh water.

Key value for chemical safety assessment

EC50 for microorganisms:
50 mg/L

Additional information

Experimental result suggests the effect concentration (EC50) for the substance Methylamine hydrochloride (CAS no. 593-51-1) was determine to be 50 mgl/L on micro organism species Microregma sp.(Ciliated Protozoa) on the basis of effect on Feeding behavior in static fresh water.

Thus based on the observed effects it is concluded that the chemical Methylamine hydrochloride (CAS no. 593-51-1) may have toxicity concern to micro organism for acute exposure period.