Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The 48-hour EC50 to Daphnia magna was determined to be 100 mg test substance/L.

Key value for chemical safety assessment

Additional information

The acute toxicity of the test substance FAT 36038/F to Daphnia magna was determined in a 48-hour static test according to the Commission Directive 92/69/EEC, Annex Part C.2, dated December 29, 1992 and the OECD Guideline for Testing of Chemicals, Section 2, No. 202, Part I, adopted April 04, 1984. The test was performed in compliance with Good Laboratory Practice Regulations.

A limit test was performed in accordance with the EEC test guideline to demonstrate that the test substance has no toxic effects on the test animals up to the concentration of nominal 100 mg test substance/l. Concentrations in excess of nominal 100 mg test substance/L have not been tested. The emulsifier Tween 80 was used (100 mg/L) for the preparation of a concentrated homogeneous stock suspension and to keep the test substance in suspension as far as possible.

The analytically determined test substance concentrations in the test media decreased from 89.1 % of the nominal value at the start of the test to 79.2 % at the end of the test, obviously caused by the low solubility of the test substance in the test water.

The reported biological results are related to the nominal test concentration as well to the mean measured test substance concentration of 84.2 mg/L (84.2 % of the nominal concentration).

The 48-hour NOEC (highest tested concentration without toxic effects after the exposure period of 48 hours), respectively the 48-hour EC 0 of FAT 36038/F to Daphnia magna was determined to be at least nominal 100 mg test substance/l (mean measured concentration: 84.2 mg/L).

Since concentrations in excess of nominal 100 mg test substance/L have not been tested, the NOEC might even be higher than this concentration. The 48-hour EC 50 of the test substance could not be determined due to the low toxicity of the test substance.