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Physical & Chemical properties

Density

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Reference
Endpoint:
density, other
Remarks:
pour density; tap density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard OECD test guidelines
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Principles of method if other than guideline:
The density is calculated from the difference in weight between the full and empty pycnometer and its volume
GLP compliance:
no
Type of method:
pycnometer method
Key result
Type:
pour density
Density:
0.572 g/cm³
Temp.:
32.2 °C
Remarks on result:
other: at 974.6 hPa atmospheric pressure
Key result
Type:
tap density
Density:
0.715 g/cm³
Temp.:
32.2 °C
Remarks on result:
other: at 974.6 hPa atmospheric pressure

CALCULATIONS:

              Parameters

        Details

          Calculated values

Average Density

1st Calculation

2ndCalculation

Pour Density of test Item (g/cm3)

m
    V

0.5882 g/cm3

0.5555 g/cm3

0.5718 g/cm3

Tap density of test Item (g/cm3)

m
    V1

0.6896 g/cm3

0.7407 g/cm3

0.7151 g/cm3

Conclusions:
The density of test item was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014.The pour density and tapped density of the test item was determine to be 0.5718 g/cm3 and 0.7151 g/cm3 at 32.2oC and  974.6hPa.
Executive summary:

The density of test item was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014.The pour density and tapped density of the test item was determine to be 0.5718 g/cm3 and 0.7151 g/cm3 at 32.2oC and  974.6hPa.

Description of key information

The density of test item was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014.The pour density and tapped density of the test item was determine to be 0.5718 g/cm3 and 0.7151 g/cm3 at 32.2oC and  974.6hPa.

Key value for chemical safety assessment

Additional information

The density of test item was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014. The pour density and tapped density of the test item was determine to be 0.5718 g/cm3 and 0.7151 g/cm3 at 32.2oC and  974.6hPa.