Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Bioaccumulation by EPI (Estimation Programs Interface) Suite
Author:
Sustainability Support Service (Europe) AB - estimated
Year:
2016
Bibliographic source:
Estimation Programs Interface Suite™ United States Environmental Protection Agency, Washington, DC, USA. version 4.1

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
BCFBAF Program (v3.00)
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): sodium 2-(2 3-dihydro-1 3-dioxo-1H-inden-2-yl)quinoline-6-sulphonate
- Molecular formula (if other than submission substance): C18H11NO5S.Na
- Molecular weight (if other than submission substance): 375.335 g/mol
- Substance type: Organic

Test organisms

Test organisms (species):
other: Fish

Study design

Route of exposure:
aqueous
Test type:
not specified
Water / sediment media type:
not specified

Test conditions

Nominal and measured concentrations:
No data
Details on estimation of bioconcentration:
No data

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3.162 L/kg
Basis:
whole body w.w.
Calculation basis:
other: estimated

Any other information on results incl. tables

Log BCF (regression-based estimate): 0.50 (BCF = 3.16 L/kg wet-wt)

Biotransformation Half-Life (days) : 0.0374 (normalized to 10 g fish)

Log BAF (Arnot-Gobas upper trophic): 0.20 (BAF = 1.59 L/kg wet-wt)

Log Kow (experimental): not available from database

Log Kow used by BCF estimates: 1.06

Equation Used to Make BCF estimate:

Log BCF = 0.50 (Ionic; Log Kow dependent)

Estimated Log BCF = 0.500 (BCF = 3.162 L/kg wet-wt)

Applicant's summary and conclusion

Conclusions:
Bioaccumulation concentration factor (BCF) value of sodium 2-(2 3-dihydro-1 3-dioxo-1H-inden-2-yl)quinoline-6-sulphonate was estimated to be 3.162 L/kg wet-wt which indicates the chemical to be non bioaccumulative in nature.
Executive summary:

Bioaccumulation concentration factor (BCF) value of sodium 2-(2 3-dihydro-1 3-dioxo-1H-inden-2-yl)quinoline-6-sulphonate was estimated to be 3.162 L/kg wet-wt which indicates the chemical to be non bioaccumulative in nature.