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EC number: 233-520-3 | CAS number: 10213-78-2
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 2010-05-28
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Justification for type of information:
- See section 13.2 for the read-across justification.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
- Deviations:
- yes
- Remarks:
- Some adjustments have been done. The concentration of the surfactant are below the CMC value, pH has been adjusted to 5-6
- GLP compliance:
- no
- Type of method:
- other: slow stir
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 3.6
- Temp.:
- 25 °C
- pH:
- 5 - 6
- Conclusions:
- The partition coefficient of the registered substance is 3.6 (log Pow).
- Executive summary:
The partition coefficient was determined to be 3.6 (log Pow) for 2,2'-(C16-18 (even numbered) alkyl imino) diethanol (PFAEO C16-18). Since the source substance is a substance with the same structure and a comparable alkyl chain length, these data are used as a worst case value for Octadecylbi(2-hydroxyethyl)amine (PFAEO C18).
Reference
The measurements were made at a pH of 5-6 and at an initial concentration of 1.83 mg/L in the water phase (about 50% of the critical micelle
concentration (CMC) in water) and at 25°C. The partition coefficient value was determined from the weighed average of the concentrations of the main components in the product listed in the table below.
Substance |
Log POW |
Bis (2 -hydroxyethyl) hydrogenated tallow alkylamine |
3.6 |
with the following results of its components: |
|
Bis (2-hydroxyethyl) dodecyl amine |
1.9 |
Bis (2-hydroxyethyl) tetradecyl amine |
3.2 |
| Bis (2-hydroxyethyl) hexadecyl amine |
4.4 |
| Bis (2-hydroxyethyl) octadecyl amine |
3.8 |
Description of key information
The partition coefficient was determined to be 3.6 (log Pow) for 2,2'-(C16-18 (even numbered) alkyl imino) diethanol (PFAEO C16-18). Since the source substance is a substance with the same structure and a comparable alkyl chain length, these data are used as a worst case value for Octadecylbi(2-hydroxyethyl)amine (PFAEO C18).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.8
- at the temperature of:
- 25 °C
Additional information
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