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EC number: 219-210-0 | CAS number: 2387-03-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound C.I. Pigment Yellow 101(CAS no 2387-03-3) and the results were predicted. The study was based on the effects of the test compound on the Scenedesmus subspicatus in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compoundC.I. Pigment Yellow 101was estimated to be 2.7442 mg/L on the basis of growth rate.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 2.744 mg/L
Additional information
Various studies of predicted data for the target chemical C.I. Pigment Yellow 101(CAS no 2387-03-3) were reviewed to summarize the following information:
72 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compoundC.I. Pigment Yellow 101(CAS no 2387-03-3) and the results were predicted. The study was based on the effects of the test compound on the Scenedesmus subspicatus in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compoundC.I. Pigment Yellow 101was estimated to be 2.7442 mg/L on the basis of growth rate.Thus, based on the EC50 value, test substance can be classified as aquatic chronic category 2 as per the criteria of CLP regulation.
72 hrs aquatic toxicity study (Danish (Q)SAR Database, 2016) was conducted to assess toxic effects of the test compoundC.I. Pigment Yellow 101(CAS no 2387-03-3) and the results were predicted. The study was based on the effects of the test compound on Pseudokirchnerella subcapitata in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound C.I. Pigment Yellow 101(CAS no 2387-03-3) was estimated to be 9.832 mg/L on the basis of growth rate.Thus based on this value it can be concluded that the substance can be classified as aquatic chronic category 2 as per the criteria of CLP regulation.
Based on the overall reported resultsof predicted data of toxicity to aquatic algae and cyanobacteria for target substance, it can be concluded that the substance can be classified asaquatic chronic category 2 as per the CLP criteria.
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