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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data is from review article or handbook

Data source

Reference
Reference Type:
review article or handbook
Title:
Acute oral toxicity of 2, 7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in rats
Author:
Registry of toxic effect of chemical substances
Year:
2016
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances)

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: as below
Principles of method if other than guideline:
Acute oral toxicity of 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in rats
GLP compliance:
not specified
Test type:
other: No data
Limit test:
no

Test material

Constituent 1
Reference substance name:
5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonic acid
EC Number:
229-413-6
EC Name:
5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonic acid
Cas Number:
6522-86-7
IUPAC Name:
5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenyldiazenyl)naphthalene-2,7-disulfonic acid
Constituent 2
Reference substance name:
2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
IUPAC Name:
2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
Details on test material:
- Name of test material (as cited in study report): 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
- Molecular formula (if other than submission substance): C19H12Cl2N6O7S2
- Molecular weight (if other than submission substance): 571.39 g/mole
- Substance type: Organic

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
No data available

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
No data available
Doses:
7460 mg/kg bw
No. of animals per sex per dose:
No data available
Control animals:
not specified
Details on study design:
No data available
Statistics:
No data available

Results and discussion

Preliminary study:
No data available
Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
7 460
Based on:
test mat.
Remarks on result:
other: 50 % mortality observed
Mortality:
No data available
Clinical signs:
No data available
Body weight:
No data available
Gross pathology:
No data available
Other findings:
No data available

Applicant's summary and conclusion

Interpretation of results:
not classified
Conclusions:
LD50 was considered to be 7460 mg/kg bw when rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- orally.
Executive summary:

In a acute oral toxicity study,rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in the concentration of7460 mg/kg bw. 50 % mortality observed in treated rat. Therefore,LD50 was considered to be7460 mg/kg bw when rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- orally.