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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data is from review article or handbook

Data source

Reference
Reference Type:
review article or handbook
Title:
Acute oral toxicity of 2, 7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in rats
Author:
Registry of toxic effect of chemical substances
Year:
2016
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances)

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: as below
Principles of method if other than guideline:
Acute oral toxicity of 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in rats
GLP compliance:
not specified
Test type:
other: No data
Limit test:
no

Test material

Constituent 1
Reference substance name:
5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonic acid
EC Number:
229-413-6
EC Name:
5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonic acid
Cas Number:
6522-86-7
IUPAC Name:
5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenyldiazenyl)naphthalene-2,7-disulfonic acid
Constituent 2
Reference substance name:
2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
IUPAC Name:
2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
Details on test material:
- Name of test material (as cited in study report): 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
- Molecular formula (if other than submission substance): C19H12Cl2N6O7S2
- Molecular weight (if other than submission substance): 571.39 g/mole
- Substance type: Organic

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
No data available

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
No data available
Doses:
7460 mg/kg bw
No. of animals per sex per dose:
No data available
Control animals:
not specified
Details on study design:
No data available
Statistics:
No data available

Results and discussion

Preliminary study:
No data available
Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
7 460
Based on:
test mat.
Remarks on result:
other: 50 % mortality observed
Mortality:
No data available
Clinical signs:
other: No data available
Gross pathology:
No data available
Other findings:
No data available

Applicant's summary and conclusion

Interpretation of results:
not classified
Conclusions:
LD50 was considered to be 7460 mg/kg bw when rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- orally.
Executive summary:

In a acute oral toxicity study,rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in the concentration of7460 mg/kg bw. 50 % mortality observed in treated rat. Therefore,LD50 was considered to be7460 mg/kg bw when rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- orally.