Registration Dossier

Administrative data

First-aid measures

Eye Contact: Flush with water while holding eyelids open for at least 15 minutes. Seek medical attention
Skin Contact: Remove contaminated clothing. Flush area with large amounts of water. Use soap. Seek
medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Wash out mouth with water. Do not
induce vomiting unless directed by medical personnel. Seek medical attention immediately.
Inhalation: Remove to fresh air and keep patient at rest. Seek medical attention immediately

Most Important Symptoms and Effects, Both Acute and Delayed
Symptoms and Effects of
No data available
Medical Conditions
Aggravated by Exposure:
None known
Indication of the Immediate Medical Attention and Special Treatment Needed
Notes to Physician: None

Fire-fighting measures

Extinguishing Media: Extinguish fires with CO2, extinguishing powder, foam, or water.
Special Hazards Arising from the Substance or Mixture
Hazardous Combustion
Formation of toxic gases is possible during heating or fire. May emit toxic fumes of oxides of
carbon and nitrogen.
Fire / Explosion Hazards: Dust can form an explosive mixture in air. Fine particles (such as dust and mists) may fuel
Advice for Fire-Fighters
During all fire fighting activities, wear appropriate protective equipment, including self-contained breathing apparatus

Accidental release measures

Personal Precautions, Protective Equipment and Emergency Procedures
Personnel involved in clean-up should wear appropriate personal protective equipment. Minimize exposure.
Environmental Precautions
Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.

Methods and Material for Containment and Cleaning Up
Measures for Cleaning /
Remove all sources of ignition. Contain the source of the spill if it is safe to do so. Collect
spilled material by a method that controls dust generation. Avoid use of a filtered vacuum to
clean spills of dry solids. Clean spill area thoroughly.
Additional Consideration for Large Spills:
Non-essential personnel should be evacuated from affected area. Report emergency
situations immediately. Clean up operations should only be undertaken by trained personnel.

Handling and storage

Precautions for Safe Handling
Ground and bond all bulk transfer equipment. Avoid open handling. Minimize dust generation. Use local exhaust ventilation or
perform work under fume hood/fume cupboard. Avoid inhalation and contact with skin, eye, and clothing. When handling, use
appropriate personal protective equipment. Wash hands and any exposed skin after removal of PPE. Releases
to the environment should be avoided. Review and implement appropriate technical and procedural waste water and waste
disposal measures to prevent occupational exposure or environmental releases. Potential points of process emissions of this
material to the atmosphere should be controlled with dust collectors, HEPA filtration systems or other equivalent controls.
Conditions for Safe Storage, Including any Incompatibilities
Storage Conditions: Store at room temperature in properly labeled containers. Keep away from heat, sparks and
Specific end use(s): Pharmaceutical intermediate

Transport information

Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all

Marine transport (IMDG)

Remarksopen allclose all

Air transport ICAO/IATA

Not regulated for shipping
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Exposure Controls
Engineering Controls: Engineering controls should be used as the primary means to control exposures. Use process
containment, local exhaust ventilation, or other engineering controls to maintain airborne levels within the OEB range.
Personal Protective
Refer to applicable national standards and regulations in the selection and use of personal protective equipment (PPE).
Hands: Wear impervious gloves to prevent skin contact.
Eyes: Wear safety glasses as minimum protection.
Skin: Wear impervious protective clothing to prevent skin contact - consider use of disposable clothing where appropriate.
Respiratory protection: If airborne exposures are within or exceed the Occupational Exposure Band (OEB) range, wear
an appropriate respirator with a protection factor sufficient to control exposures to the bottom of the OEB range.

Stability and reactivity

Reactivity: No data available
Chemical Stability: Stable under normal conditions of use.
Possibility of Hazardous Reactions
Oxidizing Properties: No data available
Conditions to Avoid: Fine particles (such as dust and mists) may fuel fires/explosions.
Incompatible Materials: As a precautionary measure, keep away from strong oxidizers
Hazardous Decomposition Products: No data available

Disposal considerations

Waste Treatment Methods: Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered. Considering the relevant known environmental and human health hazards of the material, review and implement
appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release. It is recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may
include destructive techniques for waste and wastewater.