Registration Dossier

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: The paper itself provides little information on test methodology, measured Sr-levels are not reported, and the derived end parameters are not useful for risk assessment purposes.

Data source

Reference
Reference Type:
publication
Title:
Aquatic toxicology of trace elements of coal and fly ash
Author:
Birge WJ
Year:
1978
Bibliographic source:
In: Thorpe JH, Gibbons JW (Eds.), Energy and Environmental Stress in aquatic Systems. Department of Energy Symposium Series CONT 771114

Materials and methods

Test guideline
Qualifier:
no guideline available
Guideline:
other: according to Birge and Just, 1975
Deviations:
no
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Gastrophryne carolinensis
Details on test organisms:
fertilised eggs

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
7 d

Test conditions

Hardness:
195 +/- 5.4 mg/L as CaCO3
Test temperature:
22.0 +/-1 degrees Celcius
pH:
7.4 +/- 1.0
Dissolved oxygen:
near saturation
Nominal and measured concentrations:
not reported; 10-14 concentrations were tested
Details on test conditions:
Exposure periods started upon fertilisation of the eggs and ended at 4 days post-hatching, indicating that test results should be considered as chronic tests
No further details are provided

Results and discussion

Effect concentrationsopen allclose all
Duration:
7 d
Dose descriptor:
LC50
Effect conc.:
160 µg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
element
Basis for effect:
other: mortality and teratogenity
Remarks on result:
other: 120-210
Duration:
7 d
Dose descriptor:
other: LC1
Effect conc.:
2.4 µg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
element
Basis for effect:
other: mortality and teratogenity
Remarks on result:
other: 1.0-4.6
Details on results:
Sr-levels were measured indicating that reported effect levels are based on measured values or are based on nominal values that were relevant for the actual metal concentration.
Reported statistics and error estimates:
log-probit analysis - method of Daum (1969)

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The paper itself provides little information on test methodology, measured Sr-levels are not reported, and the derived end parameters are not useful for risk assessment purposes.