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Ecotoxicological information

Toxicity to microorganisms

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Reference
Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1974
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: internal SOP Method B-10
Deviations:
not specified
Principles of method if other than guideline:
None
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
not specified
Test organisms (species):
activated sludge
Details on inoculum:
Active sewage sludge or activated sludge:
This is taken from the aerated compartment of an Husmann apparatus and has to be prepared freshly on a weekly basis.


Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
12 h
Remarks on exposure duration:
exposure duration 12-24 hours
Post exposure observation period:
Not applicable.
Test temperature:
25 ± 2 °C
Dissolved oxygen:
Not applicable
Salinity:
Not applicable
Nominal and measured concentrations:
Not specified
Details on test conditions:
See part "Any other information on materials and methods incl. tables".
Reference substance (positive control):
no
Duration:
12 h
Dose descriptor:
IC50
Effect conc.:
> 300 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: exposure duration 12-24 hours
Results with reference substance (positive control):
Not applicable
Validity criteria fulfilled:
not specified
Conclusions:
The IC50 for FAT 40069/A was found to be greater than 300 mg/L.
Executive summary:

A key toxicity study of FAT 40069/A to activated sludge was determined in a 3-hours respiration inhibition test according to the internal SOP "Method B-10". The IC50 (3 h) of the test substance FAT 40069/A is greater than 300 mg/L.

Description of key information

The IC50 for FAT 40069/A was found to be greater than 300 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
300 mg/L

Additional information

A toxicity study of FAT 40069/A to activated sludge was conducted in a 3-hours respiration inhibition test according to the internal SOP Method B-10. The IC50 (3 h) of the test substance FAT 40069/A is 300 mg/L.

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