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EC number: - | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: internal SOP Method B-10
- Deviations:
- not specified
- Principles of method if other than guideline:
- None
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- not specified
- Test organisms (species):
- activated sludge
- Details on inoculum:
- Active sewage sludge or activated sludge:
This is taken from the aerated compartment of an Husmann apparatus and has to be prepared freshly on a weekly basis. - Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 12 h
- Remarks on exposure duration:
- exposure duration 12-24 hours
- Post exposure observation period:
- Not applicable.
- Test temperature:
- 25 ± 2 °C
- Dissolved oxygen:
- Not applicable
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- Not specified
- Details on test conditions:
- See part "Any other information on materials and methods incl. tables".
- Reference substance (positive control):
- no
- Duration:
- 12 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 300 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: exposure duration 12-24 hours
- Results with reference substance (positive control):
- Not applicable
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The IC50 for FAT 40069/A was found to be greater than 300 mg/L.
- Executive summary:
A key toxicity study of FAT 40069/A to activated sludge was determined in a 3-hours respiration inhibition test according to the internal SOP "Method B-10". The IC50 (3 h) of the test substance FAT 40069/A is greater than 300 mg/L.
Reference
Description of key information
The IC50 for FAT 40069/A was found to be greater than 300 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 300 mg/L
Additional information
A toxicity study of FAT 40069/A to activated sludge was conducted in a 3-hours respiration inhibition test according to the internal SOP Method B-10. The IC50 (3 h) of the test substance FAT 40069/A is 300 mg/L.
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