Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Information from migrated NONS file as per inquiry # [06-0000024522-76-0000], permission to refer granted by ECHA
Title:
Unnamed
Year:
1991
Report date:
1991

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 84/449/EWG, B.1; OECD 401
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
4-[(3-hydroxypropyl)amino]-3-nitrophenol
EC Number:
406-305-9
EC Name:
4-[(3-hydroxypropyl)amino]-3-nitrophenol
Cas Number:
92952-81-3
Molecular formula:
C9H12N2O4
IUPAC Name:
4-[(3-hydroxypropyl)amino]-3-nitrophenol

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
other: aqueous suspension in distilled water
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male : 2000 mg/kg bw ; Number of animals : 5 ; Number of deaths : 0
Female : 2000 mg/kg bw ; Number of animals : 5 ; Number of deaths : 0
Clinical signs:
Signs of toxicity related to dose levels : none observed.
Gross pathology:
Effects on organs : none

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information
Conclusions:
Substance not classified.