Registration Dossier
Registration Dossier
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EC number: 406-305-9 | CAS number: 92952-81-3 PLAKATROT Z; ROT BN
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Information from migrated NONS file as per inquiry # [06-0000024522-76-0000], permission to refer granted by ECHA
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 84/449/EWG, B.1; OECD 401
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 4-[(3-hydroxypropyl)amino]-3-nitrophenol
- EC Number:
- 406-305-9
- EC Name:
- 4-[(3-hydroxypropyl)amino]-3-nitrophenol
- Cas Number:
- 92952-81-3
- Molecular formula:
- C9H12N2O4
- IUPAC Name:
- 4-[(3-hydroxypropyl)amino]-3-nitrophenol
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- other: aqueous suspension in distilled water
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male : 2000 mg/kg bw ; Number of animals : 5 ; Number of deaths : 0
Female : 2000 mg/kg bw ; Number of animals : 5 ; Number of deaths : 0 - Clinical signs:
- Signs of toxicity related to dose levels : none observed.
- Gross pathology:
- Effects on organs : none
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information
- Conclusions:
- Substance not classified.
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