Registration Dossier
Registration Dossier
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EC number: 223-069-0 | CAS number: 3720-16-9
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In an OECD guideline study (TG 471), conducted according to GLP, the test item celery ketone was assessed for mutagenicity by reversion to histidine independence in Salmonella typhimurium strains TA 1535, TA1537, TA98, TA100 and TA102. The test item was tested using two independent methods: direct plate incorporation and preincubation. All assays were carried out in triplicate both with and without metabolising fraction S9. Celery ketone did not show mutagenic activity in any of the strains tested both with and without S9.
Short description of key information:
Negative in all S.typhimurium strains in the absence and presence of s9.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Negative as per OECD 471 guidance and the current ECHA guidance.
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