Registration Dossier

Administrative data

eye irritation: in vitro / ex vivo
Adequacy of study:
weight of evidence
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:

Data source

Materials and methods

Test guideline
no guideline followed
Principles of method if other than guideline:
In a preliminary test the test substance shows a high adhesive strength in contact humidity, so the eyes of the study animal should be agglutinate. In due to this fact a animal study is unjustified.

Two drops of WK41 was mixed with a drop water homogeneous,. After a few second the mixiture shows high adhesive strength. The strength was so high, that a a 0.5 cm stripe of a cloth hold a weight of more than 30g.

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
highly irritating
Migrated information Criteria used for interpretation of results: expert judgment
The substance is highliy irrirating in due of eye agglutination.