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The aquatic hazard assessment of Reaction mass of bis(2-propylheptyl) hexanedioate and O6-[2,2-bis[[6-oxo-6-(2-propylheptoxy) hexanoyl]oxymethyl]butyl] O1-(2-propylheptyl) hexanedioate (List No. 942-066-1) was performed using test results with the substance itself and available data for the source substance Bis(2-propylheptyl) adipate (List No. 940-510-9, DPHA) which was used in a read across approach in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5.

The read across approach is considered valid since the source substance DPHA is the main constituent (80%) of the target substance. Thus, both substances are structurally very similar and having identical functional groups, which assumes very similar physico-chemical properties resulting in identical environmental behavior and ecotoxicity (for details see attached file and Analogue justification document in chapter 13). The second constituent of the target substance is a reaction product of DPHA and trimethylpropene (TMP). The high molecular weight (> 900 g/mole) and log Pow (> 10) of the TMP ester constituent indicate a much lower ecotoxicity of this constituent compared to DPHA. Thus, the study results for DPHA are considered to adequately cover the aquatic toxicity of the whole multi-constituent substance.

Short-term aquatic toxicity data for the substance itself (invertebrates, algae) as well as for the source substance DPHA (fish, invertebrates, algae) are available for all trophic levels. All studies were performed as limit-tests testing a 100 mg/L loading rate WAF (water-accomodatetd-fraction). None of these studies showed toxicity under the conditions used. Based on the experimental data, Reaction mass of bis(2-propylheptyl) hexanedioate and O6-[2,2-bis[[6-oxo-6-(2-propylheptoxy) hexanoyl]oxymethyl]butyl] O1-(2-propylheptyl) hexanedioate (List No. 942-066-1) is not acutely harmful to aquatic organisms in the range of its water solubility. In addition, experimental data for DPHA indicate no inhibition of the degradation activity of activated sludge when introduced to a biological treatment system.

Long-term aquatic toxicity data for the substance itself (algae) as well as for the source substance DPHA (fish, invertebrates, algae) are available for all trophic levels. No effects on growth rate, survival and reproduction up to the solubility of the substance in water were observed at all trophic groups. The available data indicate that long-term toxicity to aquatic organisms in the range of its water solubility is not to be expected.