tetrasodium 3-amino-4-{[4-({4-fluoro-6-[phenyl(2-{[2-(sulfonatooxy)ethyl]sulfonyl}ethyl)amino]-1,3,5-triazin-2-yl}amino)-2-sulfonatophenyl]diazenyl}-5-hydroxynaphthalene-2,7-disulfonate

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From September 22, 2004 to September 30, 2004

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

accepted calculation method

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: vapour pressure balance

Temp.:

20 °C

Vapour pressure:

< 0 hPa

Remarks on result:

other: Estimated vapour pressure

Temp.:

25 °C

Vapour pressure:

< 0 hPa

Remarks on result:

other: Estimated vapour pressure

Temp.:

50 °C

Vapour pressure:

0 - < 0 hPa

Remarks on result:

other: Estimated vapour pressure

- The vapour pressure was measured in the temperature range of 34 to 150°C.

- No vapour pressure of the test substance was observed in the entire range, meaning that the vapour pressure in the whole range was below the lower detection limit of 10E-5 hPa. The vapour pressure was measured at the following temperatures: 34.0, 46.0, 54.4, 66.3, 78.2, 83.7, 93.4, 102.6, 112.6, 120.2, 130.8, 139.9, 150.0 and 150.1°C. For every temperature, the vapour pressure of the test substance was <10E-5 hPa.

- Vapour pressure at 20, 25 and 50°C was calculated using the Antoine equation. Calculated vapour pressure were as follows:

 

Temperature (°C)	Vapour pressure (hPa)	Vapour pressure (Pa)
20	5.72 x 10^-11	5.72X10^-9
25	1.10x10^-10	1.10 x 10^-8
50	2.19X10^-9	2.19X10^-7

 

This was a conservative estimation of the vapour pressure of the test substance for the listed temperatures.

Since the true vapour pressure was most likely to be even much lower than this value derived from the detection limit, it may safely be assumed that the vapour pressure at the above listed temperatures was far below 10E-7 hPa (10E-5 Pa).

Conclusions:

Under the conditions of the test, the calculated vapour pressure values were 5.72 x 10E-11, 1.10x10E-10 and 2.19 X 10E-9 hPa at 20, 25 and 50°C, respectively.

Executive summary:

A study was conducted to determine the vapour pressure of the test substance according to OECD Guideline 104 and EU Method A.4, in compliance with GLP.

The determination of vapor pressure was carried out according to the effusion method (vapour pressure balance). The vapour pressure was measured at the following temperatures: 34.0, 46.0, 54.4, 66.3, 78.2, 83.7, 93.4, 102.6, 112.6, 120.2, 130.8, 139.9, 150.0 and 150.1°C. For every temperature the vapour pressure of the test substance was <10E-5 hPa.

Under the conditions of the test, the calculated vapour pressure values for the test substance were 5.72x10E-11, 1.10x10E-10 and 2.19X10E-9 hPa at 20, 25 and 50°C, respectively.

Description of key information

The calculated vapour pressure values for the test substance were 5.72 x 10E-11, 1.10x10E-10 and 2.19 X 10E-9 hPa

at 20, 25 and 50°C, respectively (Franke, 2004).

Key value for chemical safety assessment

Vapour pressure:

0 hPa

at the temperature of:

20 °C