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Toxicological information

Repeated dose toxicity: inhalation

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Administrative data

Endpoint:
repeated dose toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Schlögel
Year:
1972
Bibliographic source:
Schlögel (1972) Med. Inaug.-Diss., Würzburg, zitiert in: Toxikologisch-arbeitsmedizinische Begründungen von MAK-Werten, Verlag Chemie (1971).

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Duration of treatment / exposure:
15 moons
Frequency of treatment:
6h/day, 2days/week
Doses / concentrations
Remarks:
Doses / Concentrations:
0.5 ppm
Basis:
no data

Results and discussion

Results of examinations

Details on results:
Starke Gewichtseinbusse, schwere entzündliche Veränderungen in Nase und Lunge, erhöhte Absterberate.

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion